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Obstruction of GSH synthesis affects the lipid membrane repair ability of GPX4, increases the rate of toxic lipid free radical and ROS accumulation, and promotes lipid peroxidation, resulting in ferroptosis [1, 2]

Cagrilintide: A long-acting amylin analog for the treatment of obesity

A major aspect of EGCGs therapeutic effect is its mitochondria-centered mechanism

Baribeau, D

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(53) as a TAG lipase with a patatin homology domain that includes a combination of the G/A X G XX G and G X S X G motifs that are conserved in calcium-independent phospholipase A 2 family members